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06/13: gnu: Add r-basicstarrseq.


From: guix-commits
Subject: 06/13: gnu: Add r-basicstarrseq.
Date: Mon, 13 Nov 2023 09:10:06 -0500 (EST)

rekado pushed a commit to branch master
in repository guix.

commit 77025bd51139c74d572299f4b7b33e071cd54cd8
Author: Mădălin Ionel Patrașcu <madalinionel.patrascu@mdc-berlin.de>
AuthorDate: Mon Nov 6 12:06:42 2023 +0100

    gnu: Add r-basicstarrseq.
    
    * gnu/packages/bioconductor.scm (r-basicstarrseq): New variable.
    
    Change-Id: I88f314877ea4ab98976820a4acc337ae3a34e604
---
 gnu/packages/bioconductor.scm | 35 +++++++++++++++++++++++++++++++++++
 1 file changed, 35 insertions(+)

diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 3955f04bf1..cf7e1c07ac 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -22672,6 +22672,41 @@ Additionally, BASiCS can compare gene expression 
patterns between two or more
 pre-specified groups of cells.")
     (license license:gpl3)))
 
+(define-public r-basicstarrseq
+  (package
+    (name "r-basicstarrseq")
+    (version "1.30.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (bioconductor-uri "BasicSTARRseq" version))
+       (sha256
+        (base32 "1dw6bv1qk2bn0l3m458sqgvm3s1karh4n3431pl7r0jj2r3mr6xa"))))
+    (properties `((upstream-name . "BasicSTARRseq")))
+    (build-system r-build-system)
+    (propagated-inputs
+     (list r-genomeinfodb
+           r-genomicalignments
+           r-genomicranges
+           r-iranges
+           r-s4vectors))
+    (native-inputs (list r-knitr))
+    (home-page "https://bioconductor.org/packages/BasicSTARRseq";)
+    (synopsis "Basic peak calling on STARR-seq data")
+    (description
+     "This package implements a method that aims to identify enhancers on
+large scale.  The STARR-seq data consists of two sequencing datasets of the
+same targets in a specifc genome.  The input sequences show which regions
+where tested for enhancers.  Significant enriched peaks i.e. a lot more
+sequences in one region than in the input where enhancers in the genomic DNA
+are, can be identified.  So the approach pursued is to call peak every region
+in which there is a lot more
+(significant in a binomial model) STARR-seq signal than input signal and
+propose an enhancer at that very same position.  Enhancers then are called
+weak or strong dependent of there degree of enrichment in comparison to
+input.")
+    (license license:lgpl3)))
+
 (define-public r-basilisk-utils
   (package
     (name "r-basilisk-utils")



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